Marine biologist Henry Roth (Adam Sandler) finds the perfect woman, Lucy Whitmore (Drew Barrymore) and falls head over heels for her. But when he sees her the following day, she hasn't a clue as to who he is. Lucy suffers from a rare brain disorder that wipes her memory clean every night. Now, with the help of his friend Ula (Rob Schneider), he has to concoct new and increasingly clever ways to meet her and get her to fall for him every single day.
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